Trimethylsilyl trifluoromethanesulfonate
CAS:27607-77-8
Molecular Formular: C4H9F3O3SSi
Molecular Weight: 222.26
EINECS: 248-565-4
Boiling Point:77℃
Refractive Index:1.36
Density:1.228
Storage Condition:
Keep product under an inert gas and keep the container tightly closed. Protect the product from moisture Store at room temperature in a dry and avoid exposure to sunlight. Store locked up and away from incompatible materials such as oxidizing agents.
Application:
Trimethylsilyl trifluoromethanesulfonate is a strong Lewis acid catalyst and highly reactive silylating agent with a much greater selectivity for C-silylation than chlorotrimethylsilane. It is used to cleave t-butyl esters directly to trimethylsilyl esters, promote chemoselective reactions of acyclic acetals in the presence of cyclic acetals,promote cycloaddition of nitrones with silyl enol ethers, catalyze the conversion of aldehydes to homoallyl ethers in an Ionic Liquid and assist facile deprotection of N,O-Acetonides.Employed in the synthesis of enaminones as an Activator,one-pot synthesis of α-aminonitriles and their fluorinated analogues, and synthesis of N-vinyl derivatives of nucleobases as a Lewis acid catalyst.
Molecular Formular: C4H9F3O3SSi
Molecular Weight: 222.26
EINECS: 248-565-4
Physical Property:
Appearance:Clear colorless to pale yellow fuming liquidBoiling Point:77℃
Refractive Index:1.36
Density:1.228
Specifications:
ITEMS |
SPECIFICATIONS |
DESCRIPTION |
Clear colorless to pale yellow fuming liquid |
IDENTIFICATION BY IR |
Should confirm to standard |
ASSAY (ON AS IS BASIS) (% W/W) |
Not less than 99.0 |
Package:
25 kgs plastic drum or as per customer’s requestStorage Condition:
Keep product under an inert gas and keep the container tightly closed. Protect the product from moisture Store at room temperature in a dry and avoid exposure to sunlight. Store locked up and away from incompatible materials such as oxidizing agents.
Application:
Trimethylsilyl trifluoromethanesulfonate is a strong Lewis acid catalyst and highly reactive silylating agent with a much greater selectivity for C-silylation than chlorotrimethylsilane. It is used to cleave t-butyl esters directly to trimethylsilyl esters, promote chemoselective reactions of acyclic acetals in the presence of cyclic acetals,promote cycloaddition of nitrones with silyl enol ethers, catalyze the conversion of aldehydes to homoallyl ethers in an Ionic Liquid and assist facile deprotection of N,O-Acetonides.Employed in the synthesis of enaminones as an Activator,one-pot synthesis of α-aminonitriles and their fluorinated analogues, and synthesis of N-vinyl derivatives of nucleobases as a Lewis acid catalyst.
- Prev: Trifluoromethanesulfonic anhydride
- Next: This is the last one.